Today, my oldest child begins first grade. I can't tell you how sad and happy this makes me. I'm sad because I realize my first baby boy is truly on his way to growing up. School has him now; I don't. I can't help but predict he will need me less and less as he takes on the world in his own independent way. This makes me happy too. I am eager to see how he fares on his own, how he develops, grows, and soars. And I must admit, I am pretty thrilled about having five mornings per week all to myself -- my youngest little boy begins school today too.

On Friday, we went to six-year-old Joey's elementary school for a meet-the-teacher event. Joey was right at home. He sat at his assigned desk, did a little drawing, and snuggled up in a pile of pillows in the reading corner. I felt right at home too, after reading a parent memo about public school physical education.

Fitness has become an everyday ritual for me. Along with eating right, it's my weapon for staying healthy and keeping cancer far away. I want this same ritual for my boys. It looks like Joey will get to embrace this way of life not only at home but while in the care of his teacher too.

Axitinib is an agent that targets angiogenesis -- blood supply to a tumor. It disrupts blood vessels that grow and provide nutrients to cancer cells. Without the nutrients and oxygen supplied by blood vessels, cancer cells cannot grow or replicate.

Researchers conducted a trial to evaluate axitinib in the treatment of metastatic breast cancer. Patients were either given Taxotere or Taxotere plus axitinib. Anticancer responses were achieved in 40 percent of patients treated with the addition of axitinib to Taxotere, compared with only 23 percent of patients treated with Taxotere alone.

The researchers concluded -- that the addition of axitinib to Taxotere improves anticancer responses and delays cancer progression compared to Taxotere alone in the treatment of metastatic breast cancer.

At the 2007 meeting of the American Society of Clinical Oncology, results were presented from a clinical trial that stated -- Continuous maintenance therapy may improve survival among patients with metastatic colorectal cancer.

Maintenance therapy is used when a patient's cancer is stable and not exhibiting signs of progression. Researchers want to find a way to improve survival, but they also want to find a program that is not too intense and will have limited side effects.

This brings us to the study that was done on 202 patients with metastatic colorectal cancer. The patients were split in two groups, one group received continuous maintenance chemotherapy with a drug called Eloxatin (oxaliplatin). The second group was only treated again with chemotherapy once their cancer had started to progress.

As evidence mounts, it's becoming more and more clear that chemo brain, a mental fogginess that can result from chemotherapy, is a real concern and not just a convenient excuse cancer patients use to explain away their flighty and forgetful tendencies. It seems the brain really can suffer cognitive damage from the poisonous drugs that fight off deadly cancer cells. And sometimes, this damage is present years after treatment.

Add to chemo brain the normal aging process as well as brain conditions such as mild cognitive impairment and even schizophrenia and the brain might not stand a chance of ever remembering anything. Unless we buy into the new concept of mental training -- somewhat like physical fitness training -- in which case we may be able to bring back a level of sharpness to our lives.

Research suggests this type of training may delay mental decline. And Betty Hall, 85, who is taking a brain fitness class at her senior living complex in Illinois, says brain-enhancing activities are definitely helping her.

Hall is participating in an eight-week program where she spends one hour per day, five days per week using a computer to match words and listen for details in stories. She says it's helping her remember where she places her keys and her grocery lists -- and it's even helping her in her bridge club.

"I've won four times out of the last five at bridge club, and I think the players are going to shoot me because I keep remembering the cards people have," she said. "It's much easier for me to concentrate . . . and I brag about it everywhere I go."

One clinical professor of neurology says brain health programs will explode over the next few years because of the stunning findings on this front. One study shows relatively short training regimens, lasting just five or six weeks, improve functioning for as long as five years. And booster sessions help advance these gains. Study participants says their everyday tasks, like managing finances, are much easier after mental workouts. Another study of the computer software Hall uses shows the program shaves an average 10 years off the mental age of users.

Not all mental training is alike, and different cognitive difficulties may call for different training protocols. But the simple fact that I can work out my brain like I can work out my body gives me hope that I can possibly reverse the effects of chemotherapy on my own foggy brain, that I can one day not worry anymore that I might find my check book in the refrigerator and my cell phone in my sock drawer. Bring on the workouts!

Thanks to Bev, my brainy friend, for this story tip!

A clinical study involving 1,000 prostate cancer patients was stopped this week by Southwest Oncology Group in Michigan due to concerns the treatment may have caused leukemia in three of the participants.

The men in the study received the chemotherapy drug mitoxantrone, thought to possibly improve survival rates for those with poor prognoses following prostate surgery. But before results could be measured, leukemia struck and researchers halted the study, declaring the leukemia findings "an unacceptable risk to patients."

While the assumption is that the drug caused the leukemia -- a disease commonly associated with children and the elderly -- it's still unproved at this point.

Mitoxantrone is not a worthless drug, say some experts. Since its release a decade ago, it has been used to decrease bone pain for men with advanced prostate cancer and to treat multiple sclerosis and, ironically, adult leukemia.

A new study sheds new hopeful light on pancreatic cancer survival -- for patients 65 and older.

The study, conducted at Thomas Jefferson University and Thomas Jefferson University Hospital in Philadelphia, found patients in this age group who survive pancreatic cancer for at least five years have a better chance than patients not yet 65 at surviving another five years.

Researchers studied the records of 890 patients with pancreatic cancer who underwent the standard pancreaticoduodenectomy, or Whipple procedure. And lead researcher Charles Yeo reports that surgery can in fact extend and improve the quality of life for this population.

"Not too long ago, few lived for five years after diagnosis," he said. "Today, that not true. There's been a paradigm shift in the way we treat and think about this disease."

Additional details on this promising study can be found in the journal Surgery.

I'm headed for a Saturday morning workout with my fitness trainer. For one hour, I will physically challenge my body and emotionally charge my spirits. I will sweat and pant and if I am required to do the inner thigh exercise, I will scream. I will also whine -- it's in my nature -- and I will push, pull, bounce, balance, lift, squat, lunge, and run until it's quitting time. I will fall short on some of my exercise expectations. And I will surprise myself and exceed others. In the end, I will feel accomplished, strong, motivated, and ready to tackle the day.

I'm making a comeback. I have come back from the depths of cancer and all of its accompanying treatment, and I have invited this powerhouse of a girl to transform me. She has accepted the challenge -- and she has helped me evolve from a weak, shaky, dizzy cancer patient to a semi-strong, 5K-running breast cancer survivor with biceps that are almost visible at a close distance.

This spunky fitness girl -- also an accomplished kick boxer, wife, and mom of two little ones -- has accepted another one of my challenges. I asked her to share some of her health and fitness expertise so that we all may reap the benefits. And so she kindly extracted some important tidbits from her vast library of knowledge and concisely crafted the responses that follow.

Take it from Fitz Koehler -- exercise and healthy eating habits are key for survival. For all of us. Cancer survivors included.

Why is fitness important for everyone?

100% of the population needs to exercise in some way. For the most part, if you're not working to get stronger, you're going to get weaker. Whether it's tummy time as an infant, gym class as a kid, weight training as an adult, or short walks as a senior, in order to live well and live long, we must eat well and exercise. Plus, a fit lifestyle prevents so many horrible ailments and diseases -- heart disease, some cancers, diabetes, GERD. Who wants any of that?

The drug Vidaza (azacitadine) can be an effective treatment for those elderly patients diagnosed with acute myeloid leukemia (AML) who cannot tolerate standard treatments, according to the journal Cancer. Treatment for AML patients often starts off with induction chemotherapy followed by consolidation therapy. The induction therapy usually consists of chemotherapy that will provide complete remission. The consolidation therapy is further treatment to help prevent recurrence.

There haven't been many strides in recent years for elderly patients diagnosed with AML. Some of these patients do not seem to be able to tolerate the same treatments given to younger patients diagnosed with the disease.

Vidaza has not been extensively studied with AML but is the first drug approved by the Food and Drug Administration for myelodysplastic syndromes. It does have promise to help those who cannot tolerate standard treatments for AML. Researchers at the Western Pennsylvania Cancer Institute developed a trial that included 20 patients older than 55. Sixty percent of the 20 patients had anticancer responses. The patients that did respond to Vidaza were still alive at 15 months, compared to only 2.5 months for those who did not respond to the drug.

Hormone refractory prostate cancer is when the prostate cancer cells continue to grow after an initial period of success with hormonal therapy. Most prostate cancers are hormone dependent and require male sex hormones to grow, usually over time the prostate cancer cells develop the ability to grow in the absence of the male hormones.

In this randomized Phase III trial, men with hormone refractory prostate cancer that has metastasized will receive standard chemotherapy with the drugs docetaxel and prednisone. Half of the participants will be randomly assigned to additionally receive treatment with a monoclonal antibody called bevacizumab (Avastin).

Avastin works by stopping some cancers from developing new blood vessels. This reduces the cancer's supply of oxygen and nutrients, which causes the tumor to shrink, or at least to stop growing. Drugs that interfere with blood vessel growth in this way are called angiogenesis inhibitors or anti-angiogenics.

This Phase III trial will answer the question of whether adding bevacizaumab to docetaxal and prednisone actually does improve survival over the current standard of care.

You can join this trial that researchers will enroll 1,020 men with metatastic prostate cancer that is progressing despite hormone therapy by going to see the list of eligibility criteria.

I was in my oncologist office yesterday and noticed a new poster hanging on the wall advertising an on-line system for managing health care -- for scheduling appointments, confirming appointments, locating test results, paying bills, and more. Founded in 1999 and headquartered in Emeryville, California, RelayHealth is the premier provider of secure on-line healthcare communication services that link patients, healthcare professionals, payors, and pharmacies in matters that are medically non-urgent. The website also features news and customer stories and aims to improve the delivery and accessibility of healthcare to patients -- in a seamless manner.

I haven't done much with this service yet -- but I did take a short tour and made a simple search for my physician whose information promptly popped up on my screen. That part was easy. And once I register with a username and password, I will have more access to more information pertaining to me and my healthcare team. And you can too.

Pat Bohman is a grateful mother. Her daughter Kelsey, who was treated at Children's Hospital in Denver for leukemia, has made it through the battle. During the Christmas season of 2002, Pat thought about the children still in the hospital fighting cancer and she wanted to make them gifts. She came up with idea for the Marshmallow Launcher -- a kind of blow gun that shoots marshmallows. The children make a poster target by drawing pictures of cancer cells, the poster gets put on the wall and then the kids shoot marshmallows through a pipe-like device at the target. Marshmallow Launchers are a big hit with the kids at the hospital.

According to Bohman, the marshmallow launchers were created for the kids in isolation on the oncology unit at The Children's Hospital as a means to relieve tension, while away the long hours in isolation, and have some fun in the midst of very difficult circumstances.

But it turned out that the Marshmallow Launcher serves a medical purpose. As a respiratory device, it helps a child strengthen lung capacity. Much more fun than pinwheels and bubbles. Bohman is even thinking about adding a flow meter to the launcher as a way to measure lung capacity progress. But for the kids, it's just pure fun.

In addition, when Bohman finds out another family in her area has a child who has been diagnosed with cancer, she sets up a booth to sell the launchers. The young and young-at-heart are drawn to the fun of the Marshmallow Launcher. It has been suggested that some adults use them for interoffice communications. If you would like a Marshmallow Launcher of your own, you can visit Kelsey's Kids website where you can purchase one. Bohman makes them in the basement of her home. The profits are donated to the hospital that helped her daughter fight against cancer and win.

One of the first books I read after my breast cancer diagnosis was issued in hardback in 1986 -- 20 years ago -- and then was published again and reissued and reprinted in 1990, 1998, and 2002.While the cover has changed and perhaps some wording too, the message in this book -- Love, Medicine, & Miracles by Bernie S. Siegel, M.D. -- remains unchanged.  And it is inside the covers of this book that I keep learning that I have the capacity and power to become an exceptional patient -- despite the fact that I've been faced with a life-shattering diagnosis of cancer.

A drug prescribed for several sleep disorders including narcolepsy, depression and multiple sclerosis, has been found effective for treating the debilitating fatigue brain cancer patients suffer.

According to medical oncologists, this is very good news as attention, memory and fatigue problems and the poor quality of life that results are very common for brain cancer patients. In the study, 30 patients took Provigil, or modafinil, for two months. At the end of the study, the majority reported significant improvement in lessening fatigue. The researchers noted only mild to moderate side effects.

More and more, we hear in the news of crossover drugs, drugs used for one disease being found effective for another disease. In my personal opinion, this is not surprising. Many diseases share common characteristics. Quality of life issues are extremely important when it comes to surviving cancer.